The Food and Drug Administration has approved an injectable form of the nonsteroidal antiinflammatory drug (NSAID) ibuprofen to treat fever or pain in patients who are unable to take oral medication. Available under the trade name Caldolor, the product is for hospital use only, where it's administered as an IV infusion over an interval of 30 minutes. Because it's an NSAID, injectable ibuprofen should be used cautiously in patients who have congestive heart failure or kidney impairment, are at risk for developing blood clots, or have a history of ulceration or gastrointestinal bleeding. The product has been associated with high blood pressure and serious skin and allergic reactions; its most commonly reported adverse effects are nausea, flatulence, vomiting, and headache. See http://bit.ly/IanoA for more information.