Abstract
Since 1980, at least 9 studies have assessed the potential associations between zinc supplementation and cognitive development in human infants and children. This article provides a brief review of the literature on the roles of zinc and its proposed associations with cognition. At present, the body of evidence is insufficient to warrant recommending routine zinc supplementation to enhance cognitive performance among children. In the United States and internationally, there are few available data on zinc status or deficiency rates in children and further study is necessary to assess the efficacy of zinc supplementation, alone or in combination with other nutrients, for improving cognitive outcomes.