ABSTRACT
The number of patients treated in emergency departments across the United States for community-acquired skin and soft tissue infections is on the rise. The purpose of this article is to articulate optimal antibiotic therapy for community-acquired skin and soft tissue infections. A table format has been selected to serve as a direct reference for nurse practitioners and physician assistants. In addition, background, common pathogens, and follow-up are discussed for each disease state as well as how cost might affect nurse practitioner's and physician assistant's antibiotic selection.