Comparative economic evaluations with both indirect community and direct patient preferences are seldom reported in the same study in patients with the same condition when estimating the quality-adjusted life years (QALYs) gained with an intervention. The objectives of this secondary analysis were to estimate incremental cost-utility ratios (ICURs in 2005 US dollars) using both indirect community (Quality of Well-being, QWB) and direct patient (Time Trade-Off, TTO) preferences in a randomized clinical trial of cardiac rehabilitation (n = 93 to cardiac rehabilitation; n = 95 to usual care) and to present both QWB and TTO cost-utility planes and cost-utility acceptability curves as a way for informing decisions about the provision of cardiac rehabilitation after myocardial infarction. The QWB-derived estimates demonstrate a modest amount of quality-adjusted gain per patient (0.011 QALYs) at a cost of $73,630/QALY gained with a .41 probability of cardiac rehabilitation being cost-effective at the conventional threshold of $50,000/QALY. The TTO-derived estimates demonstrate larger, but not significantly different, estimates of quality-adjusted gain per patient (0.040 QALYs) at a lower cost of $20,750/QALY gained with a .74 probability of rehabilitation being cost-effective at the conventional threshold of $50,000/QALY gained. The cost-utility analyses suggest that the added costs of cardiac rehabilitation may be worth the added benefits from the policy perspective and probably are worth the health gains from the clinician/patient decision-makers' perspectives. The cost-utility planes and cost-utility acceptability curves described in this study complement those recently published in other studies.