Keywords

Case study, Cutaneous Leishmaniasis, Teledermatology, Tropical Medicine, Infectious Disease

 

Authors

  1. Grossman, Julie
  2. Guccione, Jack

Abstract

ABSTRACT: Teledermatology is a term to describe the provision of dermatologic medical services through telecommunication technology. This is a teledermatology case of seven nonhealing lesions located on the right arm and left leg.

 

Article Content

In the store-and-forward teledermatology modality, there is a transfer of patient medical information electronically (including history and visual data) obtained in one location to a provider who is in another location (Roman & Jacob, 2014; Warshaw, Gravely, & Nelson, 2010) The construct of the TeleDermViewPoint column is such that cases are presented in a standardized teledermatology reader format reflective of an actual teledermatology report.

 

TELEDERMATOLOGY READER REPORT1

History

Chief complaint

Presenting for diagnosis and therapeutic options of a lesion.

 

History of present illness

A 50-year-old man presents with seven, nonitchy, nonpainful ulcerating lesions on his right arm and left leg. The lesions developed 1 month after returning from a visit to southern Italy and have persisted for 5 months. Prior treatment: triamcinolone cream without improvement. His primary symptom: nonhealing lesions. Prior biopsy: none. Other significant laboratory/study findings: none. He has no personal or family history of skin cancer or melanoma.

 

IMAGE QUALITY ASSESSMENT

Satisfactory.

 

TELEDERMATOLOGY IMAGING READER REPORT

Interpretation of Images

Lesion A: Findings

The presented nonhealing, right arm lesion is concerning for an infectious process (Figure 1).

  
Figure 1 - Click to enlarge in new windowFIGURE 1. Right upper arm showing a single nonhealing ulcerating lesion.

Lesion B: Findings

The presented nonhealing, left leg lesions are concerning for an infectious process (Figure 2).

  
Figure 2 - Click to enlarge in new windowFIGURE 2. Left leg showing three nonhealing ulcerating lesions.

RECOMMENDATIONS

Given the history and clinical presentation, a biopsy is indicated to direct the management. The nonhealing nature of these lesions is concerning.

 

Type of Visit

Refer to dermatology for face-to-face evaluation, culture, and tissue biopsy.

 

CLINCAL PEARL

In teledermatology, the key is to utilize the history and physical examination findings to discern the diagnosis. Given the patient's recent travel to Italy, a cutaneous infectious disease is high in the differential. This case was presented to teledermatology where a biopsy revealed that the patient had contracted cutaneous leishmaniasis (CL).

 

Leishmaniasis is a vector-born infection caused by the flagellate parasite species Leishmania and is transmitted by the female phlebotomine sand-fly bite (Melby, 1991). Infections are categorized into four major human diseases: localized CL, diffuse CL, mucocutaneous leishmaniasis, and visceral leishmaniasis. Localized CL takes a subclinical, self-limited course primarily affecting immunocompetent hosts. It is furthermore classified into Old World (Mediterranean basin, Central Africa, Southern Europe, and Southern Asia) and New World (Central and South America, and parts of Texas) infections. Because of the patient's recent return from Italy, we believe he contracted an Old-World form of leishmaniasis, with the most common forms being L. tropica and L. major (Oumeish, 1999).

 

Clinically, ulcerating lesions are nonitchy and painless with variable morphology, which contributes to its frequent misdiagnosis (Dowlati, 1996). Histology shows hallmark Leishman-Donovan bodies inside the cytoplasm of histiocytes. First-line pharmacologic treatments of CL include topical and oral antifungal agents. Cryotherapy and thermotherapy have also been shown to be effective; however, oral miltefosine is the only approved treatment by the Food and Drug Administration for CL (Ruiter, Zerp, Bartelink, van Blitterswijk, & Verheij, 2003). The reader is referred to key sources for additional information on therapeutics (Malek & Ghosn, 2012). Indeed, prompt biopsy of new skin lesions in travelers returning from endemic areas is warranted to rule out CL.

 

REFERENCES

 

Dowlati Y. (1996). Treatment of cutaneous leishmaniasis (Old World). Clin Dermatol, 14(5), 513-517. [Context Link]

 

Malek J. M., & Ghosn S. H. (2012). Chapter 206. Leishmaniasis and other protozoan infections. In Goldsmith L. A., Katz S. I., Gilchrest B. A., Paller A. S., Leffell D. J., & Wolff K. (Eds.), Fitzpatrick's dermatology in general medicine, 8e. New York, NY: The McGraw-Hill Companies. [Context Link]

 

Melby P. C. (1991). Experimental leishmaniasis in humans: Review. Reviews of Infectious Diseases, 13(5), 1009-1017. [Context Link]

 

Oumeish O. Y. (1999). Cutaneous leishmaniasis: A historical perspective. Clinics in Dermatology, 17(3), 249-254. [Context Link]

 

Roman M., & Jacob S. E. (2014). Teledermatology: virtual access to quality dermatology care and beyond. Journal of the Dermatology Nurses' Association, 6(6), 288-289. doi:10.1097/jdn.0000000000000093 [Context Link]

 

Ruiter G. A., Zerp S. F., Bartelink H., van Blitterswijk W. J., & Verheij M. (2003). Anti-cancer alkyl-lysophospholipids inhibit the phosphatidylinositol 3-kinase-Akt/PKB survival pathway. Anti-Cancer Drugs, 14(2), 167-173. doi:10.1097/01.cad.0000054974.31252.f7 [Context Link]

 

Warshaw E. M., Gravely A. A., & Nelson D. B. (2010). Accuracy of teledermatology/teledermoscopy and clinic-based dermatology for specific categories of skin neoplasms. Journal of the American Academy of Dermatology, 63(2), 348-352. doi:10.1016/j.jaad.2009.10.037 [Context Link]

 

1The standardized teledermatology reader report format is available for authors on the journal's Web site (http://www.jdnaonline.com) and on the submissions Web site online at http://journals.lww.com/jdnaonline/Documents/Teledermatology%20Column%20Template. [Context Link]