Abstract
This review explores the importance of the course of time in the development of deep vein thrombosis and its connection to prophylaxis in total hip replacement, emphasizing the impact on nursing practice. It examines the application of expanded use of low-molecular-weight heparin as an effective option versus warfarin. The principles behind once-daily dosing for prevention of thromboembolic disease in total hip replacement are presented, as well as the benefits of extended prophylaxis. Finally, a series of initiatives provides orthopaedic nurses with an action plan to expand their role in clinical decision-making with other members of the healthcare team.