Abstract
Nerve entrapment conditions and peripheral neuropathies are sometimes related to injurious events, toxicosis, and repetitive microtrauma to soft tissue and nerve structures. An interesting theory concerning peripheral entrapment neuropathy has been discussed in the literature. This theory is called the double crush syndrome. This article briefly discusses the biologic/metabolic, structural, toxicogenic, and vasculopathic rationale for the pathogenesis of double crush syndrome.