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BLADDER CANCER

Transurethral Resection of Bladder Tumors Using PK Button Vaporization Electrode or Monopolar Loop Electrocautery in Treating Patients With Bladder Cancer

  
National Cancer Inst... - Click to enlarge in new windowNational Cancer Institute. National Cancer Institute

Status: Active

 

Phase: Phase IV

 

Type: Treatment

 

Age: 18 to 89

 

Trial IDs: WCI2119-11, NCI-2013-00065, IRB00053735, NCT01567462

 

Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain after Surgery in Patients With Bladder Cancer

 

Status: Not yet active

 

Phase: Phase IV

 

Type: Health services research, Supportive care

 

Age: 18 and over

 

Trial IDs: 4B-14-4, NCI-2015-00279, NCT02438852

 

An Expanded Access Study of Atezolizumab in Participants With Locally Advanced or Metastatic Urothelial Carcinoma After Failure With Platinum-Containing Chemotherapy

 

Status: Not yet active

 

Phase: Phase IV

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: ML29725, NCI-2015-01995, NCT02589717

 

Standard or Extended Pelvic Lymphadenectomy in Treating Patients Undergoing Surgery for Invasive Bladder Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: S1011, NCI-2011-02604, CDR0000686574, SWOG-S1011, NCT01224665

 

Goal-Directed Fluid Management or Standard Fluid Therapy in Reducing Delayed Bowel Function in Patients With Bladder Cancer Undergoing Surgery

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 21 and over

 

Trial IDs: 14-069, NCI-2014-01262, NCT02145871

 

Surgery or Non-surgical Management in Treating Patients With Intra-abdominal Cancer and Bowel Obstruction

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: S1316, NCI-2014-01497, SWOG/S1316, NCT02270450

 

Safety and Efficacy of CG0070 Oncolytic Virus Regimen for High Grade Non-Muscle Invasive Bladder Cancer After BCG Failure

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: BOND 2 version 3.7, NCI-2015-01830, BOND 2 version 3.4, NCT02365818

 

A Study of Ramucirumab (LY3009806) Plus Docetaxel in Participants With Urothelial Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: 15679, NCI-2015-02085, 2014-003655-66, I4T-MC-JVDC, NCT02426125

 

Biologic Mesh in Preventing Hernia in Patients With Bladder Cancer Undergoing Radical Cystectomy With Ileal Conduit Diversion

 

Status: Not yet active

 

Phase: Phase III

 

Type: Supportive care

 

Age: Not specified

 

Trial IDs: 4B-14-2, NCI-2015-00278, NCT02439060

 

Vicinium Treatment for Subjects With Non-muscle Invasive Bladder Cancer Previously Treated With BCG

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: VB4-845-02-IIIA, NCI-2015-01369, NCT02449239

 

A Phase III Study of Atezolizumab Treatment Versus Observation as Adjuvant Therapy in Patients With PD-L1 Positive, High Risk Muscle Invasive Bladder Cancer After Cystectomy [IMvigor010]

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: WO29636, NCI-2015-01334, 2014-005603-25, NCT02450331

 

A Study of Blue Light Flexible Cystoscopy With Cysview in the Detection of Bladder Cancer in the Surveillance Setting

 

Status: Active

 

Phase: Phase III

 

Type: Diagnostic

 

Age: 18 and over

 

Trial IDs: PC B308/13, NCI-2015-01925, NCT02560584

 

BRAIN TUMOR

Light Sedation or Intubated General Anesthesia in Reducing Complications and Length of Hospital Stay in Patients With Brain Cancer Undergoing Craniotomy

 

Status: Active

 

Phase: Phase IV

 

Type: Supportive care, Treatment

 

Age: 19 and over

 

Trial IDs: OSU-12161, NCI-2014-01110, 2014C0007, NCT02193568

 

Perampanel in Lowering the Incidence of Seizures in Patients With Primary Glioma

 

Status: Active

 

Phase: Phase IV

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: Pro00055609, NCI-2015-00365, NCT02363933

 

Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma Multiforme

 

Status: Active

 

Phase: Phase III, Phase II

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: A071102, NCI-2014-00616, CALGB-A071102, NCT02152982

 

P2/3 Randomized Study of Toca 511 & Toca FC Versus SOC in Subjects Undergoing Surgery for Recurrent GBM/AA

 

Status: Active

 

Phase: Phase III, Phase II

 

Type: Treatment

 

Age: 18 to 75

 

Trial IDs: Tg 511-15-01, NCI-2015-01577, NCT02414165

 

Study of a Drug [DCVax(R)-L] to Treat Newly Diagnosed GBM Brain Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 to 65

 

Trial IDs: 020221, NCI-2010-00822, NCT00045968

 

Radiation Therapy or Radiation Therapy and Temozolomide in Treating Patients With Newly Diagnosed Anaplastic Glioma or Low Grade Glioma

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Tissue collection/Repository, Treatment

 

Age: 18 and over

 

Trial IDs: N0577, NCI-2011-01915, CDR0000640442, EORTC-26081-22086, EudraCT-2008-007295-14, NCCTG-N0577, NCT00887146

 

Armodafinil in Reducing Cancer-Related Fatigue in Patients With High-Grade Glioma

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: A221101, NCI-2012-02020, N10C3, NCT01781468

 

A Study of the Effectiveness and Safety of Nivolumab Compared to Bevacizumab and of Nivolumab With or Without Ipilimumab in Glioblastoma Patients

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: CA209-143, NCI-2014-00328, 2013-003738-34, NCT02017717

 

Carboplatin With or Without Vincristine Sulfate in Treating Younger Patients With Previously Untreated Low Grade Glioma

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 21 and younger

 

Trial IDs: LCH 14C03, NCI-2015-01146, LGG-14C03, 2014-15932, NCT02455245

 

A Phase 3, Pivotal Trial of VB-111 Plus Bevacizumab vs. Bevacizumab in Patients With Recurrent Glioblastoma (GLOBE)

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: VB-111-215, NCI-2015-01344, NCT02511405

 

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: ICT-107-301, NCI-2015-01811, NCT02546102

 

CHRONIC MYELOGENOUS LEUKEMIA

Safety And Efficacy Study Of Bosutinib In Patients With Philadelphia Chromosome Positive Chronic Myeloid Leukemia Previously Treated With One Or More Tyrosine Kinase Inhibitors

 

Status: Active

 

Phase: Phase IV

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: B1871039, NCI-2014-02251, 2013-003250-25, NCT02228382

 

Dasatinib in Treating Patients With Philadelphia Chromosome Positive or BCR-ABL1 Positive Early Chronic Phase Chronic Myelogenous Leukemia

 

Status: Active

 

Phase: Phase IV

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 2015-1040, NCI-2016-00362, NCT02689440

 

Eltrombopag Olamine in Treating Thrombocytopenia in Patients With Chronic Myeloid Leukemia or Myelofibrosis Receiving Tyrosine Kinase Therapy

 

Status: Active

 

Phase: Phase III, Phase II

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: 2011-0319, NCI-2011-03336, NCT01428635

 

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT)

 

Status: Active

 

Phase: Phase III

 

Type: Prevention

 

Age: 18 and over

 

Trial IDs: 0113-CL-1004, NCI-2013-01949, 2013-000903-18, NCT01877655

 

Alemtuzumab Before Donor Stem Cell Transplant in Treating Patients With Hematologic Diseases

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 70 and under

 

Trial IDs: HIMSUM, NCI-2012-00639, NCT00058825

 

Study of Cordycepin Plus Pentostatin in Patients With Refractory TdT-Positive Leukemia

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: OV06-001, NCI-2010-00051, NCT00709215

 

Low-Dose Donor Bone Marrow Transplant in Treating Patients With Hematologic Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 6 montha to 70

 

Trial IDs: J1055, NCI-2011-00377, NCT01203722

 

Dasatinib and Decitabine in Treating Patients With Accelerated or Blastic Phase Chronic Myelogenous Leukemia

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 2011-0333, NCI-2012-00014, CA180357, NCT01498445

 

Laboratory-Treated T Cells in Treating Patients With High-Risk Relapsed Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia Previously Treated With Donor Stem Cell Transplant

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: Not specified

 

Trial IDs: 2498.00, NCI-2011-03362, 2498, NCT01640301

 

Conventional and Regulatory T Cells in Treating Patients With Advanced Hematologic Malignancies Undergoing T Cell-Depleted Donor Stem Cell Transplant

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 13 to 60

 

Trial IDs: BMT236, NCI-2011-03025, NCT01660607

 

Inotuzumab Ozogamicin, Fludarabine Phosphate, Bendamustine Hydrochloride, and Rituximab before Donor Stem Cell Transplant in Treating Patients With Lymphoid Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 to 70

 

Trial IDs: 2012-0265, NCI-2012-02072, NCT01664910

 

Azacitidine in Treating Patients Undergoing Matched Unrelated Stem Cell Transplant

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 to 65

 

Trial IDs: 201303012, NCI-2012-03105, NCT01747499

 

Ruxolitinib for Chronic Myeloid Leukemia (CML) With Minimal Residual Disease (MRD)

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 2012-0697, NCI-2013-00551, NCT01751425

 

Donor Natural Killer Cells and Donor Stem Cell Transplant in Treating Patients With High Risk Myeloid Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 65 and under

 

Trial IDs: 2012-0819, NCI-2013-00993, RP110553-P3, NCT01823198

 

AP1903 and Genetically Modified Donor T Cells after Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 to 65

 

Trial IDs: 2012-0501, NCI-2013-01666, NCT01875237

 

ENDOMETRIAL CANCER

Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer

 

Status: Temporarily closed

 

Phase: Phase III, Phase II

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: GOG-0286B, NCI-2013-02284, NCT02065687

 

Chemotherapy or Observation in Stage I-II Intermediate or High Risk Endometrial Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: Over 18

 

Trial IDs: ENGOT-EN2-DGCG/EORTC55102, NCI-2014-00983, 2010-023081-52, NCT01244789

 

Surgery or Non-surgical Management in Treating Patients With Intra-abdominal Cancer and Bowel Obstruction

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: S1316, NCI-2014-01497, SWOG/S1316, NCT02270450

 

Olaparib Treatment in Relapsed Germline Breast Cancer Susceptibility Gene (BRCA) Mutated Ovarian Cancer Patients Who Have Progressed at Least 6 Months After Last Platinum Treatment and Have Received at Least 2 Prior Platinum Treatments.

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: D0816C00010, NCI-2015-01077, NCT02282020

 

Epidural Anesthesia Within an Enhanced Recovery Pathway in Reducing Pain in Patients Undergoing Gynecologic Surgery

 

Status: Active

 

Phase: Phase III

 

Type: Biomarker/Laboratory analysis, Supportive care

 

Age: 18 and over

 

Trial IDs: UW14030, NCI-2015-00395, NCT02423876

 

Negative Pressure Wound Therapy in Caring for Women after Abdominal Surgery

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: 15-309, NCI-2016-00514, NCT02682316

 

A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: BBI608-201, NCI-2014-01566, NCT01325441

 

Tisotumab Vedotin (HuMax(R)-TF-ADC) Safety Study in Patients With Solid Tumors

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: GEN701, NCI-2014-01166, NCT02001623

 

Phase 1-2 Study of Onapristone in Patients With Progesterone Receptor Expressing Cancers

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: ARN-AR18-CT-101, NCI-2016-00136, NCT02052128

 

A Phase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of Pembrolizumab (MK-3475) in Combination With Epacadostat (INCB024360) in Subjects With Selected Cancers (INCB 24360-202 / MK-3475-037 / KEYNOTE-037/ ECHO-202)

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: INCB 24360-202, NCI-2015-01316, NCT02178722

 

HODGKIN LYMPHOMA

Autologous Peripheral Blood Stem Cell Transplant in Treating Patients With Lymphoma

 

Status: Active

 

Phase: Phase III, Phase II

 

Type: Treatment

 

Age: Under 70

 

Trial IDs: MT 2004-24, NCI-2010-01414, 0508M72589, 2005LS048, UMN-2005LS048, UMN-0508M72589, UMN-MT2004-24, NCT00345865

 

Double Cord Versus Haploidentical (BMT CTN 1101)

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 to 70

 

Trial IDs: BMTCTN1101, NCI-2014-00307, 715, 5U24CA076518, NCT01597778

 

A Study to Evaluate a Therapeutic Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seropositive Recipients Undergoing Allogeneic, Hematopoietic Cell Transplant (HCT)

 

Status: Active

 

Phase: Phase III

 

Type: Prevention

 

Age: 18 and over

 

Trial IDs: 0113-CL-1004, NCI-2013-01949, 2013-000903-18, NCT01877655

 

A Study to Evaluate the Efficacy and Safety of Rivaroxaban Venous Thromboembolism (VTE) Prophylaxis in Ambulatory Cancer Participants

 

Status: Active

 

Phase: Phase III

 

Type: Prevention

 

Age: 18 and over

 

Trial IDs: CR107047, NCI-2016-00410, 2015-001630-21, 39039039STM4001, NCT02555878

 

Study of Pembrolizumab (MK-3475) vs. Brentuximab Vedotin in Participants With Relapsed or Refractory Classical Hodgkin Lymphoma (MK-3475-204/KEYNOTE-204)

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 3475-204, NCI-2016-00839, 2015-005053-12, 163337, NCT02684292

 

Alemtuzumab Before Donor Stem Cell Transplant in Treating Patients With Hematologic Diseases

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 70 and under

 

Trial IDs: HIMSUM, NCI-2012-00639, NCT00058825

 

Safety and Efficacy Study of TNX-650 to Treat Refractory Hodgkin's Lymphoma

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: Over 18

 

Trial IDs: TNX-650.101, NCI-2010-00951, NCT00441818

 

Autologous or Donor Cytotoxic T-Lymphocytes in Treating Patients With Epstein-Barr Virus-Positive Hematologic Malignancy

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: Any age

 

Trial IDs: ALCI, NCI-2012-00653, H-9936, NCT00671164, NCT00070226, 9936-ALCI, NCT00062868

 

Low-Dose Donor Bone Marrow Transplant in Treating Patients With Hematologic Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 6 montha to 70

 

Trial IDs: J1055, NCI-2011-00377, NCT01203722

 

Yttrium Y 90 Daclizumab and Combination Chemotherapy before Stem Cell Transplant in Treating Patients With Recurrent or Refractory Hodgkin's Lymphoma

 

Status: Temporarily closed

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 12-C-0003, NCI-2013-01512, P11859, 120003, NCT01468311

 

NASOPHARYNGEAL CANCER

DNA

 

Status: Active

 

Phase: Phase III, Phase II

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: NRG-HN001, NCI-2014-00635, RTOG-1305, NCT02179164, NCT02135042

 

Acupuncture in Treating Dry Mouth Caused by Radiation Therapy in Patients With Head and Neck Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: Not specified

 

Trial IDs: MDA-04-01, NCI-2011-02073, WFU 97115, CDR0000674208, WF-97115, NCT01141231

 

A Study of Pembrolizumab (MK-3475) for First Line Treatment of Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck (MK-3475-048/KEYNOTE-048)

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: 3475-048, NCI-2015-00270, 2014-003698-41, NCT02358031

 

Modified Dakin's Solution in Reducing Radiation-Induced Dermatitis in Patients With Head and Neck Cancer Undergoing Radiation Therapy

 

Status: Active

 

Phase: Phase III

 

Type: Supportive care

 

Age: 18 and over

 

Trial IDs: ENT0042,

 

NCI-2015-00176, 32439,

 

NCT02369835

 

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: D4193C00002, NCI-2015-01842, NCT02369874

 

Study of Nivolumab in Combination With Ipilimumab Compared to the Standard of Care (Extreme Study Regimen) as First Line Treatment in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: CA209-651, NCI-2016-01450, 2016-000725-39, NCT02741570

 

Caphosol for the Reduction of Mucositis in Patients Receiving Radiation Therapy for Head and Neck Cancer

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Supportive care, Treatment

 

Age: 18 and over

 

Trial IDs: 603EUSA03, NCI-2010-01741, NCT00901732

 

Cetuximab, EGFR Antisense DNA, and Radiation Therapy in Treating Patients With Stage III-IV Squamous Cell Cancer of the Head and Neck

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: UPCI 06-121, NCI-2013-00329, NCT00903461

 

A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: BBI608-201, NCI-2014-01566, NCT01325441

 

Combination Chemotherapy With or Without Veliparib in Treating Patients With Stage IV Head and Neck Cancer

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: A091101, NCI-2012-02009, NCT01711541

 

OSTEOSARCOMA

Prophylactic Antibiotic Regimens in Tumor Surgery (PARITY)

 

Status: Active

 

Phase: Phase III

 

Type: Prevention

 

Age: 15 and over

 

Trial IDs: GHRT01, NCI-2014-02097, NCT01479283

 

Combination Chemotherapy and Fixed or Flexible Administration of Filgrastim in Treating Younger Patients With Cancer

 

Status: Active

 

Phase: Phase III

 

Type: Treatment

 

Age: 1 to 25

 

Trial IDs: 2013-062, NCI-2013-02001, NCT01987596

 

A Study of BBI608 Administered With Paclitaxel in Adult Patients With Advanced Malignancies

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Treatment

 

Age: 18 and over

 

Trial IDs: BBI608-201, NCI-2014-01566, NCT01325441

 

To Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 6 months to 21 years

 

Trial IDs: ABI-007-PST-001, NCI-2015-00737, NCT01962103

 

OKT3/Humanized 3F8 Bispecific Antibody-Activated T Lymphocytes, Aldesleukin, and Sargramostim in Treating Younger Patients with GD2-Positive Metastatic, Recurrent or Refractory Solid Tumors

 

Status: Temporarily closed

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 13 months to 29 years

 

Trial IDs: 2013-171, NCI-2014-01149, 1403012875, NCT02173093

 

Nivolumab with or without Ipilimumab in Treating Younger Patients with Recurrent or Refractory Solid Tumors or Sarcomas

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 12 months to 30 years

 

Trial IDs: ADVL1412, NCI-2014-01222, NCT02304458

 

PLX3397 and Sirolimus in Treating Patients with Sarcoma or Malignant Peripheral Nerve Sheath Tumors That Cannot Be Removed by Surgery

 

Status: Active

 

Phase: Phase II, Phase I

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 18 and over

 

Trial IDs: AAAO6059, NCI-2015-01768, NCT02584647

 

Iodine I 131 Monoclonal Antibody 3F8 in Treating Patients with GD2-Expressing Central Nervous System and Leptomeningeal Neoplasms

 

Status: Active

 

Phase: Phase II

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: Any age

 

Trial IDs: 05-122, NCI-2016-00874, MSKCC-05122, NCT00445965

 

Study of Pazopanib in the Treatment of Osteosarcoma Metastatic to the Lung

 

Status: Active

 

Phase: Phase II

 

Type: Biomarker/Laboratory analysis, Treatment

 

Age: 16 and over

 

Trial IDs: AWACMOS1102, NCI-2013-01371, ACORN AWACMOS1102, NCT01759303

 

Hypofractionated Stereotactic Radiation Therapy in Treating Younger Patients with Metastatic Sarcomas of Bony Sites

 

Status: Active

 

Phase: Phase II

 

Type: Treatment

 

Age: Greater than 3 to less than or equal to 40

 

Trial IDs: J1367, NCI-2013-02433, NA_00070109, NCT01763970