New Drug Indications - April 2022


remdesivir

Veklury

Pharmaceutical company: Gilead Sciences, Inc.

NEW INDICATION & DOSAGE

Treatment of non-hospitalized patients with mild-to-moderate coronavirus disease 2019 (COVID-19) at high risk for progression to severe COVID-19, including hospitalization or death

Adults and children age 12 and older, weighing 40 kg or more: Initiate therapy as soon as possible after diagnosis and within 7 days of symptom onset with 200-mg IV infusion on day 1, followed by 100-mg IV infusion once daily on days 2 and 3.

Adjust-a-dose:Consider discontinuing the drug if ALT level increases to greater than 10 × the upper limit of normal. Discontinue if ALT elevation is accompanied by signs or symptoms of liver inflammation.

Released: April 2022

Nursing Drug Handbook

© 2022 Wolters Kluwer
 

risankizumab-rzaa

Skyrizi

Pharmaceutical company: AbbVie Inc.

NEW INDICATION & DOSAGE

Active psoriatic arthritis

Adults: 150 mg (two 75-mg injections) subcut at week 0, week 4, and every 12 weeks thereafter, alone or in combination with nonbiologic disease-modifying antirheumatic drugs.

Released: April 2022

Nursing Drug Handbook

© 2022 Wolters Kluwer
 

secnidazole

Solosec

Pharmaceutical company: Lupin Pharmaceuticals, Inc.

NEW INDICATION & DOSAGE

Bacterial vaginosis

Females age 12 and older: One single dose of 2 g PO.

Trichomoniasis

Children age 12 and older: One single dose of 2 g PO. Treat sexual partners with same dose at same time.

Released: April 2022

Nursing Drug Handbook

© 2022 Wolters Kluwer