Abstract
Stress in nurses is multifocal, pervasive, and persistent. They practice in a contemporary heath care environment characterized by rapid change, the ongoing integration of novel technologies, and interpersonal challenges. Relationships with patients and families pose unique dilemmas related to witnessing anguish and trauma over time. Interventions are needed to counter the affective demands of nurse caregiving. To this end, national initiatives have been proposed to outline general work setting enhancements promoting well-being. Stressor-specific interventions have also been identified. The goal of this article is to provide an overview of the macro (organizational) recommendations for change and a micro (practice setting) blueprint of potential interventions to promote nurse well-being.