Abstract
Abstract: Asthma-COPD overlap (ACO) presents in persons, especially adults, with persistent airflow limitation along with clinical symptoms reflective of both asthma and chronic obstructive pulmonary disease (COPD). It includes multiple clinical phenotypes with different underlying pathophysiology. Patients with ACO typically have a worse clinical course than those with asthma or COPD alone. This article provides an overview of diagnosis and management of this underrecognized condition.