Abstract
Purpose: The aim of the study was to propose and test a quality of life model among Korean patients with amyotrophic lateral sclerosis (ALS) using structural equation modeling.
Design: A cross-sectional study was performed.
Methods: Data from 184 patients with ALS were collected from two university hospitals in Seoul and Busan, South Korea, between June and December 2018.
Findings: The modified model indices indicated adequate data fit. Quality of life predictors were social support, physical functional status, depression, and general health perception.
Conclusion: This study improved the understanding of quality of life for Korean patients with ALS, including complex direct and indirect relationships among quality of life factors.
Clinical Relevance: Depression was identified as the most influential factor in this population; hence, early assessment and timely intervention for depression are essential for better quality of life in patients with ALS.