Keywords

chorea, Huntington disease, huntingtin, neurodegenerative disease, HTT

 

Authors

  1. Cummins, Angela BSN, RN
  2. Eggert, Julia PhD, GNP-BC, AOCN
  3. Pruitt, Rosanne PhD, FNP-BC
  4. Collins, Julianne S. PhD

Abstract

This article reviews the normal function of the huntingtin gene, mutation-induced changes in the gene product (protein), possible causes of Huntington disease, and associated symptoms. An educational tool with recommendations the practitioner can use for interventions and counseling with patients and their families is also included.