February 2006, Volume 36 Number 2 , p 22 - 23
D'ARCY, YVONNE CRNP, CNS, MS
RECENT REPORTS from the Food and Drug Administration (FDA) have cited both selective and nonselective nonsteroidal anti-inflammatory drugs (NSAIDs), not just the cyclooxygenase (COX-2) inhibitors, as posing cardiovascular risks. What do we really know about NSAIDs and their dangers? What should we tell our patients when they ask for information about NSAIDs? I'll explore these issues here. For more on the two types of NSAIDs, see A closer look at NSAIDs .
What do we know?
Much of the research data on the risks of NSAIDs is conflicting and inconclusive. However, these points are fairly certain:
* In patients with no cardiovascular risk factors, short-term NSAID use for acute pain doesn't seem to increase the risk of stroke or myocardial infarction (MI), according to the FDA. * All NSAIDs can cause cardiovascular adverse events such as stroke and MI. According to the FDA, research supports the view that the cardiovascular ...