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September 2011, Volume 41 Number 9 , p 13 - 13



A booster vaccine has been approved to prevent tetanus, diphtheria, and pertussis in people age 65 and older. Boostrix, which is given as a single-dose booster injection, had already been approved for use in children and adults ages 10 through 64. It's the first single-dose vaccine approved to prevent all three diseases in older adults.A study involving 1,300 adults age 65 and older demonstrated the safety and effectiveness of Boostrix in older adults. The antibody levels among those given the booster were comparable to levels in infants who received a similar vaccine for pertussis prevention. The antibody resp-onses to the tetanus and diphtheria components were compared with a licensed tetanus and diphtheria vaccine and were found comparable. Common adverse -reactions reported by participants were headache, fatigue, and pain at the injection site.The incidence of pertussis has been increasing in the United States since 2007, with many outbreaks occurring among older patients in long-term-care

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