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September 2010, Volume 40 Number 9 , p 14 - 14


  • Michael R. Cohen ScD, MS, RPH


A unit dose cup of levetiracetam 100 mg/mL from VistaPharm contains 500 mg in the 5 mL cup, but because the volume statement is far removed from the concentration, the total amount could be easily misread. Mistakenly giving 5 cups for a 500 mg dose would actually deliver 2,500 mg. Levetiracetam is an antiepileptic drug available as a liquid.Because of the high risk of a miscalculation, the Institute for Safe Medication Practices (ISMP) has asked VistaPharm to look into redesigning the label to put the volume and concentration information in closer proximity.Zavesca, marketed in the United States as miglustat capsules, is also sold in other parts of the world, but with a difference: The overseas version of the drug contains escitalopram, known in the United States as Lexapro.Miglustat is used to treat adults with mild to moderate type 1 Gaucher disease when enzyme replacement therapy isn't an option. Escitalopram, a selective serotonin reuptake inhibitor, is indicated to treat major

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