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June 2010, Volume 40 Number 6 , p 17 - 17



A new study indicates that postmenopausal women who regularly take aspirin, nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen may have lower sex steroid hormone concentrations, possibly reducing the risk of breast or ovarian cancer.Researchers examined analgesic use and estrogen levels of 740 postmenopausal women in the Nurses' Health Study. The women reported their analgesic use in 1988 or 1990 and provided blood samples in 1989 to 1990. Women who used NSAIDs at least 15 days/month had significantly lower estradiol levels compared with women who didn't take NSAIDs.According to the study's authors, regular analgesic users may have lower estrogen levels than nonusers, which could reduce the risk of ovarian or breast cancer.Source: Gates MA, Tworoger SS, Eliassen AH, Missmer SA, Hankinson SE. Analgesic use and sex steroid hormone concentrations in postmenopausal women. Cancer Epidemiol Biomarkers Prev. 2010;19(4):1033–1041.Salsalate, an atypical

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