Acute high calcium intake also increases fat oxidation; sensitivity analysis reveals weak effect
THURSDAY, June 28 (HealthDay News) -- Chronic high calcium intake in adults increases fat oxidation and is particularly effective in those who habitually consume less than 700 mg/day of calcium, according to a study published online June 19 in Obesity Reviews.
Javier T. Gonzalez, of Northumbria University in Newcastle, U.K., and colleagues conducted a meta-analysis of eight randomized controlled trials investigating the effects of high calcium intake on fat oxidation in adult humans and meeting the authors' criteria for inclusion.
The researchers found that chronic high calcium intake correlated with a increase in fat oxidation. The standardized mean difference was 0.42, which corresponded to an 11 percent increase, with low heterogeneity noted. This effect was most prominent in individuals who had a habitual low calcium intake of less than 700 mg/day. Acute high calcium intake correlated with increased fat oxidation, with a standardized mean difference of 0.41. Heterogeneity was low and sensitivity analysis indicated that the effect was weak.
"In conclusion, chronic (>7 day) high calcium (~1,300 versus ~488 mg/d−1) intake increases fat oxidation, which may contribute to the fat loss benefits of a high-calcium, energy-restricted diet," the authors write. "The effect is most profound in individuals with a low habitual calcium intake, and may be more effective under energy restriction. Acute calcium supplementation (in a single meal) also appears to increase fat oxidation; however, further work is required to substantiate this."
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